Targeting pericytes with a PDGF-B aptamer in human ovarian carcinoma models

PURPOSE: On the basis of the known role of platelet-derived growth factor (PDGF)-BB/PDGF receptor (PDGFR) β in pericyte regulation, highly specific inhibitors of this target are needed. We tested the efficacy of a highly selective aptamer against PDGF-B with or without anti-VEGF therapy in ovarian c...

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Hauptverfasser: Lu, Chunhua, Shahzad, Mian M.K., Moreno-Smith, Myrthala, Lin, Yvonne G., Jennings, Nicholas B., Allen, Julie K., Landen, Charles N., Mangala, Lingegowda S., Armaiz-Pena, Guillermo N., Schmandt, Rosemarie, Nick, Alpa M., Stone, Rebecca L., Jaffe, Robert B., Coleman, Robert L., Sood, Anil K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155813/
https://ncbi.nlm.nih.gov/pubmed/20009575
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