ATP11B mediates platinum resistance in ovarian cancer

Platinum compounds display clinical activity against a wide variety of solid tumors; however, resistance to these agents is a major limitation in cancer therapy. Reduced platinum uptake and increased platinum export are examples of resistance mechanisms that limit the extent of DNA damage. Here, we...

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Hauptverfasser: Moreno-Smith, Myrthala, Halder, J.B., Meltzer, Paul S., Gonda, Tamas A., Mangala, Lingegowda S., Rupaimoole, Rajesha, Lu, Chunhua, Nagaraja, Archana S., Gharpure, Kshipra M., Kang, Yu, Rodriguez-Aguayo, Cristian, Vivas-Mejia, Pablo E., Zand, Behrouz, Schmandt, Rosemarie, Wang, Hua, Langley, Robert R., Jennings, Nicholas B., Ivan, Cristina, Coffin, Jeremy E., Armaiz, Guillermo N., Bottsford-Miller, Justin, Kim, Sang Bae, Halleck, Margaret S., Hendrix, Mary J.C., Bornman, William, Bar-Eli, Menashe, Lee, Ju-Seog, Siddik, Zahid H., Lopez-Berestein, Gabriel, Sood, Anil K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635722/
https://ncbi.nlm.nih.gov/pubmed/23585472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65425
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