Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression

MicroRNAs (miRNAs) are small RNA molecules that affect cellular processes by controlling gene expression. Recent studies have shown that hypoxia downregulates Drosha and Dicer, key enzymes in miRNA biogenesis, causing a decreased pool of miRNAs in cancer, and resulting in increased tumor growth and...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Oncogene
Main Authors: Rupaimoole, Rajesha, Ivan, Cristina, Yang, Da, Gharpure, Kshipra M., Wu, Sherry Y., Pecot, Chad V., Previs, Rebecca A., Nagaraja, Archana S., Armaiz-Pena, Guillermo N, McGuire, Michael, Pradeep, Sunila, Mangala, Lingegowda S., Rodriguez-Aguayo, Cristian, Huang, Li, Bar-Eli, Menashe, Zhang, Wei, Lopez-Berestein, Gabriel, Calin, George A., Sood, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931989/
https://ncbi.nlm.nih.gov/pubmed/26725326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.492
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares