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Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression
MicroRNAs (miRNAs) are small RNA molecules that affect cellular processes by controlling gene expression. Recent studies have shown that hypoxia downregulates Drosha and Dicer, key enzymes in miRNA biogenesis, causing a decreased pool of miRNAs in cancer, and resulting in increased tumor growth and...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4931989/ https://ncbi.nlm.nih.gov/pubmed/26725326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.492 |
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