Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression

MicroRNAs (miRNAs) are small RNA molecules that affect cellular processes by controlling gene expression. Recent studies have shown that hypoxia downregulates Drosha and Dicer, key enzymes in miRNA biogenesis, causing a decreased pool of miRNAs in cancer, and resulting in increased tumor growth and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncogene
Egile Nagusiak: Rupaimoole, Rajesha, Ivan, Cristina, Yang, Da, Gharpure, Kshipra M., Wu, Sherry Y., Pecot, Chad V., Previs, Rebecca A., Nagaraja, Archana S., Armaiz-Pena, Guillermo N, McGuire, Michael, Pradeep, Sunila, Mangala, Lingegowda S., Rodriguez-Aguayo, Cristian, Huang, Li, Bar-Eli, Menashe, Zhang, Wei, Lopez-Berestein, Gabriel, Calin, George A., Sood, Anil K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931989/
https://ncbi.nlm.nih.gov/pubmed/26725326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.492
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