Convergent systems-based approaches identify a role for OCIAD1 in Alzheimer's disease

Tekijä Geertsma, Haley M., Rousseaux, Maxime W.C.
Julkaisussa EBioMedicine (2020)

The role of TDP-43 mislocalization in amyotrophic lateral sclerosis

Tekijä Suk, Terry R., Rousseaux, Maxime W. C.
Julkaisussa Mol Neurodegener (2020)

Progress toward an integrated understanding of Parkinson’s disease

Tekijä Rousseaux, Maxime W.C., Shulman, Joshua M., Jankovic, Joseph
Julkaisussa F1000Res (2017)

CRISPRcloud: a secure cloud-based pipeline for CRISPR pooled screen deconvolution

Tekijä Jeong, Hyun-Hwan, Kim, Seon Young, Rousseaux, Maxime W C, Zoghbi, Huda Y, Liu, Zhandong
Julkaisussa Bioinformatics (2017)

Beta-binomial modeling of CRISPR pooled screen data identifies target genes with greater sensitivity and fewer false negatives

Tekijä Jeong, Hyun-Hwan, Kim, Seon Young, Rousseaux, Maxime W.C., Zoghbi, Huda Y., Liu, Zhandong
Julkaisussa Genome Res (2019)

Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma

Tekijä Tan, Qiumin, Brunetti, Lorenzo, Rousseaux, Maxime W. C., Lu, Hsiang-Chih, Wan, Ying-Wooi, Revelli, Jean-Pierre, Liu, Zhandong, Goodell, Margaret A., Zoghbi, Huda Y.
Julkaisussa Proc Natl Acad Sci U S A (2018)

The Parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage

Tekijä Aleyasin, Hossein, Rousseaux, Maxime W. C., Phillips, Maryam, Kim, Raymond H., Bland, Ross J., Callaghan, Steve, Slack, Ruth S., During, Matthew J., Mak, Tak W., Park, David S.
Julkaistu 2007

Essential Role of Cytoplasmic cdk5 and Prx2 in Multiple Ischemic Injury Models, In Vivo

Tekijä Rashidian, Juliet, Rousseaux, Maxime W., Venderova, Katerina, Qu, Dianbo, Callaghan, Steve M., Phillips, Maryam, Bland, Ross J., During, Matthew J., Mao, Zixu, Slack, Ruth S., Park, David S.
Julkaistu 2009

Regulation of the VHL/HIF-1 Pathway by DJ-1

Tekijä Parsanejad, Mohammad, Zhang, Yi, Qu, Dianbo, Irrcher, Isabella, Rousseaux, Maxime W.C., Aleyasin, Hossein, Kamkar, Fatemeh, Callaghan, Steve, Slack, Ruth S., Mak, Tak W., Lee, Stephen, Figeys, Daniel, Park, David S.
Julkaisussa J Neurosci (2014)

Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease

Tekijä Rousseaux, Maxime W. C., Marcogliese, Paul C., Qu, Dianbo, Hewitt, Sarah J., Seang, Sarah, Kim, Raymond H., Slack, Ruth S., Schlossmacher, Michael G., Lagace, Diane C., Mak, Tak W., Park, David S.
Julkaistu 2012

An Anatomically Resolved Mouse Brain Proteome Reveals Parkinson Disease-relevant Pathways

Tekijä Jung, Sung Yun, Choi, Jong Min, Rousseaux, Maxime W. C., Malovannaya, Anna, Kim, Jean J., Kutzera, Joachim, Wang, Yi, Huang, Yin, Zhu, Weimin, Maity, Suman, Zoghbi, Huda Yahya, Qin, Jun
Julkaisussa Mol Cell Proteomics (2017)

DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway

Tekijä Aleyasin, Hossein, Rousseaux, Maxime W. C., Marcogliese, Paul C., Hewitt, Sarah J., Irrcher, Isabella, Joselin, Alvin P., Parsanejad, Mohammad, Kim, Raymond H., Rizzu, Patrizia, Callaghan, Steve M., Slack, Ruth S., Mak, Tak W., Park, David S.
Julkaistu 2010

DJ-1 Interacts with and Regulates Paraoxonase-2, an Enzyme Critical for Neuronal Survival in Response to Oxidative Stress

Tekijä Parsanejad, Mohammad, Bourquard, Noam, Qu, Dianbo, Zhang, Yi, Huang, En, Rousseaux, Maxime W. C., Aleyasin, Hossein, Irrcher, Isabella, Callaghan, Steve, Vaillant, Dominique C., Kim, Raymond H., Slack, Ruth S., Mak, Tak W., Reddy, Srinivasa T., Figeys, Daniel, Park, David S.
Julkaistu 2014

Doublecortin-like Kinase 1 Regulates α-Synuclein Levels and Toxicity

Tekijä Vázquez-Vélez, Gabriel E., Gonzales, Kristyn A., Revelli, Jean-Pierre, Adamski, Carolyn J., Alavi Naini, Fatemeh, Bajić, Aleksandar, Craigen, Evelyn, Richman, Ronald, Heman-Ackah, Sabrina M., Wood, Matthew J.A., Rousseaux, Maxime W.C., Zoghbi, Huda Y.
Julkaisussa J Neurosci (2020)

BAG2 Gene-mediated Regulation of PINK1 Protein Is Critical for Mitochondrial Translocation of PARKIN and Neuronal Survival

Tekijä Qu, Dianbo, Hage, Ali, Don-Carolis, Katie, Huang, En, Joselin, Alvin, Safarpour, Farzaneh, Marcogliese, Paul C., Rousseaux, Maxime W. C., Hewitt, Sarah J., Huang, Tianwen, Im, Doo-Soon, Callaghan, Steve, Dewar-Darch, Danielle, Figeys, Daniel, Slack, Ruth S., Park, David S.
Julkaisussa J Biol Chem (2015)

Reduction of Nuak1 decreases tau and reverses phenotypes in a tauopathy mouse model

Tekijä Lasagna-Reeves, Cristian A., de Haro, Maria, Hao, Shuang, Park, Jeehye, Rousseaux, Maxime W.C., Al-Ramahi, Ismael, Jafar-Nejad, Paymaan, Vilanova-Velez, Luis, See, Lauren, De Maio, Antonia, Nitschke, Larissa, Wu, Zhenyu, Troncoso, Juan C., Westbrook, Thomas F., Tang, Jianrong, Botas, Juan, Zoghbi, Huda.Y.
Julkaisussa Neuron (2016)

ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism

Tekijä Rousseaux, Maxime W.C., Tschumperlin, Tyler, Lu, Hsiang-Chih, Lackey, Elizabeth P., Bondar, Vitaliy V., Wan, Ying-Wooi, Tan, Qiumin, Adamski, Carolyn J., Friedrich, Jillian, Twaroski, Kirk, Chen, Weili, Tolar, Jakub, Henzler, Christine, Sharma, Ajay, Bajić, Aleksandar, Lin, Tao, Duvick, Lisa, Liu, Zhandong, Sillitoe, Roy V., Zoghbi, Huda Y., Orr, Harry T.
Julkaisussa Neuron (2018)

Dual targeting of brain region‐specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1

Tekijä Lee, Won‐Seok, Lavery, Laura, Rousseaux, Maxime W C, Rutledge, Eric B, Jang, Youjin, Wan, Ying‐Wooi, Wu, Sih‐Rong, Kim, Wonho, Al‐Ramahi, Ismael, Rath, Smruti, Adamski, Carolyn J, Bondar, Vitaliy V, Tewari, Ambika, Soleimani, Shirin, Mota, Samantha, Yalamanchili, Hari K, Orr, Harry T, Liu, Zhandong, Botas, Juan, Zoghbi, Huda Y
Julkaisussa EMBO J (2021)

A Druggable Genome Screen Identifies Modifiers of α-Synuclein Levels via a Tiered Cross-Species Validation Approach

Tekijä Rousseaux, Maxime W.C., Vázquez-Vélez, Gabriel E., Al-Ramahi, Ismael, Jeong, Hyun-Hwan, Bajić, Aleksandar, Revelli, Jean-Pierre, Ye, Hui, Phan, Emily T., Deger, Jennifer M., Perez, Alma M., Kim, Ji-Yoen, Lavery, Laura A., Xu, Qikia, Li, Mamie Z., Kang, Hyojin, Kim, Jean J., Shulman, Joshua M., Westbrook, Thomas F., Elledge, Stephen J., Liu, Zhandong, Botas, Juan, Zoghbi, Huda Y.
Julkaisussa J Neurosci (2018)