Conversations With Dr. Oleh Hornykiewicz, Founding Father of the Dopamine Era in Parkinson's: How Do You Wish to Be Remembered?

por Schlossmacher, Michael G., Graybiel, Ann M.
Publicado no Mov Disord (2020)

Parkin-Dependent Degradation of the F-Box Protein Fbw7β Promotes Neuronal Survival in Response to Oxidative Stress by Stabilizing Mcl-1

por Ekholm-Reed, Susanna, Goldberg, Matthew S., Schlossmacher, Michael G., Reed, Steven I.
Publicado em 2013

Aggregated α-Synuclein Mediates Dopaminergic Neurotoxicity In Vivo

por Periquet, Magali, Fulga, Tudor, Myllykangas, Liisa, Schlossmacher, Michael G., Feany, Mel B.
Publicado no J Neurosci (2007)

Modelling idiopathic Parkinson disease as a complex illness can inform incidence rate in healthy adults: the P(R)EDIGT score

por Schlossmacher, Michael G., Tomlinson, Julianna J., Santos, Goncalo, Shutinoski, Bojan, Brown, Earl G., Manuel, Douglas, Mestre, Tiago
Publicado no Eur J Neurosci (2016)

Towards translational therapies for multiple system atrophy

por Kuzdas-Wood, Daniela, Stefanova, Nadia, Jellinger, Kurt A., Seppi, Klaus, Schlossmacher, Michael G., Poewe, Werner, Wenning, Gregor K.
Publicado em 2014

Novel One-step Immunoassays to Quantify α-Synuclein: APPLICATIONS FOR BIOMARKER DEVELOPMENT AND HIGH-THROUGHPUT SCREENING

por Bidinosti, Michael, Shimshek, Derya R., Mollenhauer, Brit, Marcellin, David, Schweizer, Tatjana, Lotz, Gregor P., Schlossmacher, Michael G., Weiss, Andreas
Publicado em 2012

A First Tetraplex Assay for the Simultaneous Quantification of Total α-Synuclein, Tau, β-Amyloid(42) and DJ-1 in Human Cerebrospinal Fluid

por Kruse, Niels, Schlossmacher, Michael G., Schulz-Schaeffer, Walter J., Vanmechelen, Eugeen, Vanderstichele, Hugo, El-Agnaf, Omar M., Mollenhauer, Brit
Publicado no PLoS One (2016)

Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains

por Baulac, Stéphanie, Lu, Hope, Strahle, Jennifer, Yang, Ting, Goldberg, Matthew S, Shen, Jie, Schlossmacher, Michael G, Lemere, Cynthia A, Lu, Qun, Xia, Weiming
Publicado em 2009

Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo

por Cullen, Valerie, Lindfors, Maria, Ng, Juliana, Paetau, Anders, Swinton, Erika, Kolodziej, Piotr, Boston, Heather, Saftig, Paul, Woulfe, John, Feany, Mel B, Myllykangas, Liisa, Schlossmacher, Michael G, Tyynelä, Jaana
Publicado em 2009

α-Synuclein in human cerebrospinal fluid is principally derived from neurons of the central nervous system

por Mollenhauer, Brit, Trautmann, Ellen, Otte, Birgit, Ng, Juliana, Spreer, Annette, Lange, Peter, Sixel-Döring, Friederike, Hakimi, Mansoureh, VonSattel, Jean-Paul, Nussbaum, Robert, Trenkwalder, Claudia, Schlossmacher, Michael G.
Publicado em 2012

Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease

por Rousseaux, Maxime W. C., Marcogliese, Paul C., Qu, Dianbo, Hewitt, Sarah J., Seang, Sarah, Kim, Raymond H., Slack, Ruth S., Schlossmacher, Michael G., Lagace, Diane C., Mak, Tak W., Park, David S.
Publicado em 2012

DMS as an orthogonal separation to LC/ESI/MS/MS for quantifying isomeric cerebrosides in plasma and cerebrospinal fluid

por Xu, Hongbin, Boucher, Frederic R., Nguyen, Thao T., Taylor, Graeme P., Tomlinson, Julianna J., Ortega, Roberto A., Simons, Brigitte, Schlossmacher, Michael G., Saunders-Pullman, Rachel, Shaw, Walt, Bennett, Steffany A. L.
Publicado no J Lipid Res (2019)

GATA transcription factors directly regulate the Parkinson's disease-linked gene α-synuclein

por Scherzer, Clemens R., Grass, Jeffrey A., Liao, Zhixiang, Pepivani, Imelda, Zheng, Bin, Eklund, Aron C., Ney, Paul A., Ng, Juliana, McGoldrick, Meghan, Mollenhauer, Brit, Bresnick, Emery H., Schlossmacher, Michael G.
Publicado em 2008

Expansion of the Parkinson disease-associated SNCA-Rep1 allele upregulates human α-synuclein in transgenic mouse brain

por Cronin, Kenneth D., Ge, Dongliang, Manninger, Paul, Linnertz, Colton, Rossoshek, Anna, Orrison, Bonnie M., Bernard, David J., El-Agnaf, Omar M.A., Schlossmacher, Michael G., Nussbaum, Robert L., Chiba-Falek, Ornit
Publicado em 2009

CNS expression of glucocerebrosidase corrects α-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy

por Sardi, S. Pablo, Clarke, Jennifer, Kinnecom, Cathrine, Tamsett, Thomas J., Li, Lingyun, Stanek, Lisa M., Passini, Marco A., Grabowski, Gregory A., Schlossmacher, Michael G., Sidman, Richard L., Cheng, Seng H., Shihabuddin, Lamya S.
Publicado em 2011

Parkin Localizes to the Lewy Bodies of Parkinson Disease and Dementia with Lewy Bodies

por Schlossmacher, Michael G., Frosch, Matthew P., Gai, Wei Ping, Medina, Miguel, Sharma, Nutan, Forno, Lysia, Ochiishi, Tomoyo, Shimura, Hideki, Sharon, Ronit, Hattori, Nobutaka, Langston, J. William, Mizuno, Yoshikuni, Hyman, Bradley T., Selkoe, Dennis J., Kosik, Kenneth S.
Publicado em 2002

Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson’s disease

por Kim, Kwang Soo, Marcogliese, Paul C., Yang, Jungwoo, Callaghan, Steve M., Resende, Virginia, Abdel-Messih, Elizabeth, Marras, Connie, Visanji, Naomi P., Huang, Jana, Schlossmacher, Michael G., Trinkle-Mulcahy, Laura, Slack, Ruth S., Lang, Anthony E., Park, David S.
Publicado no Proc Natl Acad Sci U S A (2018)

Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson’s disease

por Eidson, Lori N., Kannarkat, George T., Barnum, Christopher J., Chang, Jianjun, Chung, Jaegwon, Caspell-Garcia, Chelsea, Taylor, Peggy, Mollenhauer, Brit, Schlossmacher, Michael G., Ereshefsky, Larry, Yen, Mark, Kopil, Catherine, Frasier, Mark, Marek, Kenneth, Hertzberg, Vicki S., Tansey, Malú G.
Publicado no J Neuroinflammation (2017)

Molecular markers of early Parkinson's disease based on gene expression in blood

por Scherzer, Clemens R., Eklund, Aron C., Morse, Lee J., Liao, Zhixiang, Locascio, Joseph J., Fefer, Daniel, Schwarzschild, Michael A., Schlossmacher, Michael G., Hauser, Michael A., Vance, Jeffery M., Sudarsky, Lewis R., Standaert, David G., Growdon, John H., Jensen, Roderick V., Gullans, Steven R.
Publicado em 2007

Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures

por Hakimi, Mansoureh, Selvanantham, Thirumahal, Swinton, Erika, Padmore, Ruth F., Tong, Youren, Kabbach, Ghassan, Venderova, Katerina, Girardin, Stephen E., Bulman, Dennis E., Scherzer, Clemens R., LaVoie, Matthew J., Gris, Denis, Park, David S., Angel, Jonathan B., Shen, Jie, Philpott, Dana J., Schlossmacher, Michael G.
Publicado em 2011