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Regulation of the VHL/HIF-1 Pathway by DJ-1

DJ-1 (PARK7) is a gene linked to autosomal recessive Parkinson disease (PD). We showed previously that DJ-1 loss sensitizes neurons in models of PD and stroke. However, the biochemical mechanisms underlying this protective role are not completely clear. Here, we identify Von Hippel Lindau (VHL) prot...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Parsanejad, Mohammad, Zhang, Yi, Qu, Dianbo, Irrcher, Isabella, Rousseaux, Maxime W.C., Aleyasin, Hossein, Kamkar, Fatemeh, Callaghan, Steve, Slack, Ruth S., Mak, Tak W., Lee, Stephen, Figeys, Daniel, Park, David S.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2014
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608259/
https://ncbi.nlm.nih.gov/pubmed/24899725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1244-13.2014
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