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Playing Tag with HIF: The VHL Story
Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene product pVHL is the cause of inherited VHL disease and is associated with sporadic kidney cancer. pVHL is found in a multiprotein complex with elongins B/C, Cul2, and Rbx1 forming an E3 ubiquitin ligase complex called VEC. This modul...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC161365/ https://ncbi.nlm.nih.gov/pubmed/12488577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/S1110724302205057 |
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