Загрузка...
Evolution of metazoan oxygen-sensing involved a conserved divergence of VHL affinity for HIF1α and HIF2α
Duplication of ancestral hypoxia-inducible factor (HIF)α coincided with the evolution of vertebrate species. Paralogs HIF1α and HIF2α are the most well-known factors for modulating the cellular transcriptional profile following hypoxia. However, how the processes of natural selection acted upon the...
Сохранить в:
| Опубликовано в: : | Nat Commun |
|---|---|
| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2019
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6650433/ https://ncbi.nlm.nih.gov/pubmed/31337753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11149-1 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|