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At the crossroads of oxygen and iron sensing: hepcidin control of HIF-2α
Hepcidin is the master regulator of iron metabolism. It plays a key role in the regulation of iron transport across the duodenal epithelium, which in turn is dependent on the oxygen-regulated transcription factor hypoxia-inducible factor 2α (HIF-2α). In this issue of the JCI, Schwartz and colleagues...
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| Udgivet i: | J Clin Invest |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6307931/ https://ncbi.nlm.nih.gov/pubmed/30530987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI125509 |
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