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HIF-2α, but not HIF-1α, promotes iron absorption in mice
HIF transcription factors (HIF-1 and HIF-2) are central mediators of cellular adaptation to hypoxia. Because the resting partial pressure of oxygen is low in the intestinal lumen, epithelial cells are believed to be mildly hypoxic. Having recently established a link between HIF and the iron-regulato...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673882/ https://ncbi.nlm.nih.gov/pubmed/19352007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38499 |
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