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HIF1α and HIF2α: sibling rivalry in hypoxic tumor growth and progression
Hypoxia inducible factors (HIFs) are broadly expressed in human cancers, and HIF1α and HIF2α were previously suspected of promoting tumor progression through largely overlapping functions. However, this relatively simple model has now been challenged in light of recent data from genome-wide analyses...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401912/ https://ncbi.nlm.nih.gov/pubmed/22169972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3183 |
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