HIF-2α regulates Oct-4: effects of hypoxiaon stem cell function, embryonic development, and tumor growth

The division, differentiation, and function of stem cells and multipotent progenitors are influenced by complex signals in the microenvironment, including oxygen availability. Using a genetic “knock-in” strategy, we demonstrate that targeted replacement of the oxygen-regulated transcription factor H...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Covello, Kelly L., Kehler, James, Yu, Hongwei, Gordan, John D., Arsham, Andrew M., Hu, Cheng-Jun, Labosky, Patricia A., Simon, M. Celeste, Keith, Brian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2006
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1410808/
https://ncbi.nlm.nih.gov/pubmed/16510872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1399906
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