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HIF-2α regulates Oct-4: effects of hypoxiaon stem cell function, embryonic development, and tumor growth
The division, differentiation, and function of stem cells and multipotent progenitors are influenced by complex signals in the microenvironment, including oxygen availability. Using a genetic “knock-in” strategy, we demonstrate that targeted replacement of the oxygen-regulated transcription factor H...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1410808/ https://ncbi.nlm.nih.gov/pubmed/16510872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1399906 |
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