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Acute postnatal ablation of Hif-2α results in anemia

Adaptive transcriptional responses to oxygen deprivation (hypoxia) are mediated by the hypoxia-inducible factors (HIFs), heterodimeric transcription factors composed of two basic helix–loop–helix–PAS family proteins. The transcriptional activity of HIF is determined by the hypoxic stabilization of t...

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Detalhes bibliográficos
Main Authors: Gruber, Michaela, Hu, Cheng-Jun, Johnson, Randall S., Brown, Eric J., Keith, Brian, Simon, M. Celeste
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892942/
https://ncbi.nlm.nih.gov/pubmed/17284606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608382104
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