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Acute postnatal ablation of Hif-2α results in anemia
Adaptive transcriptional responses to oxygen deprivation (hypoxia) are mediated by the hypoxia-inducible factors (HIFs), heterodimeric transcription factors composed of two basic helix–loop–helix–PAS family proteins. The transcriptional activity of HIF is determined by the hypoxic stabilization of t...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1892942/ https://ncbi.nlm.nih.gov/pubmed/17284606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608382104 |
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