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The N-Terminal Transactivation Domain Confers Target Gene Specificity of Hypoxia-inducible Factors HIF-1α and HIF-2α

The basic helix-loop-helix-Per-ARNT-Sim–proteins hypoxia-inducible factor (HIF)-1α and HIF-2α are the principal regulators of the hypoxic transcriptional response. Although highly related, they can activate distinct target genes. In this study, the protein domain and molecular mechanism important fo...

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Bibliografiset tiedot
Päätekijät: Hu, Cheng-Jun, Sataur, Aneesa, Wang, Liyi, Chen, Hongqing, Simon, M. Celeste
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Cell Biology 2007
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043574/
https://ncbi.nlm.nih.gov/pubmed/17804822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-05-0419
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