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Maternal intestinal HIF-2α is necessary for sensing iron demands of lactation in mice

The mechanisms that are essential for the maintenance of nutrient status in breast milk are unclear. Our data demonstrate that the intestine via hypoxia-inducible factor (HIF)-2α is an essential regulatory mechanism for maintaining the quality of breast milk. During lactation, intestinal HIF-2α is h...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ramakrishnan, Sadeesh K., Anderson, Erik R., Martin, Angelical, Centofanti, Brook, Shah, Yatrik M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507236/
https://ncbi.nlm.nih.gov/pubmed/26124130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504891112
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