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Maternal intestinal HIF-2α is necessary for sensing iron demands of lactation in mice

The mechanisms that are essential for the maintenance of nutrient status in breast milk are unclear. Our data demonstrate that the intestine via hypoxia-inducible factor (HIF)-2α is an essential regulatory mechanism for maintaining the quality of breast milk. During lactation, intestinal HIF-2α is h...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Ramakrishnan, Sadeesh K., Anderson, Erik R., Martin, Angelical, Centofanti, Brook, Shah, Yatrik M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507236/
https://ncbi.nlm.nih.gov/pubmed/26124130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504891112
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