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Playing Tag with HIF: The VHL Story

Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene product pVHL is the cause of inherited VHL disease and is associated with sporadic kidney cancer. pVHL is found in a multiprotein complex with elongins B/C, Cul2, and Rbx1 forming an E3 ubiquitin ligase complex called VEC. This modul...

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Autors principals: Leung, Sherri K., Ohh, Michael
Format: Artigo
Idioma:Inglês
Publicat: 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC161365/
https://ncbi.nlm.nih.gov/pubmed/12488577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/S1110724302205057
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