Corticostriatal synaptic function in mouse models of Huntington's disease: early effects of huntingtin repeat length and protein load

Por Milnerwood, Austen J, Raymond, Lynn A
Publicado em 2007

Influence of cortical synaptic input on striatal neuronal dendritic arborization and sensitivity to excitotoxicity in corticostriatal coculture

Por Buren, Caodu, Tu, Gaqi, Parsons, Matthew P., Sepers, Marja D., Raymond, Lynn A.
Publicado no J Neurophysiol (2016)

Decreasing Levels of the cdk5 Activators, p25 and p35, Reduces Excitotoxicity in Striatal Neurons

Por Park, Kevin H.J., Lu, Ge, Fan, Jing, Raymond, Lynn A., Leavitt, Blair R.
Publicado em 2012

Striatal Synaptic Dysfunction and Hippocampal Plasticity Deficits in the Hu97/18 Mouse Model of Huntington Disease

Por Kolodziejczyk, Karolina, Parsons, Matthew P., Southwell, Amber L., Hayden, Michael R., Raymond, Lynn A.
Publicado em 2014

Genetic rescue of CB(1) receptors on medium spiny neurons prevents loss of excitatory striatal synapses but not motor impairment in HD mice

Por Naydenov, Alipi V., Sepers, Marja D., Swinney, Katie, Raymond, Lynn A., Palmiter, Richard, Stella, Nephi
Publicado em 2014

Pathophysiology of Huntington’s Disease: Time-Dependent Alterations in Synaptic and Receptor Function

Por Raymond, Lynn A., André, Véronique M., Cepeda, Carlos, Gladding, Clare M., Milnerwood, Austen J., Levine, Michael S.
Publicado em 2011

An Automated Home-Cage System to Assess Learning and Performance of a Skilled Motor Task in a Mouse Model of Huntington’s Disease

Por Woodard, Cameron L., Bolaños, Federico, Boyd, James D., Silasi, Gergely, Murphy, Timothy H., Raymond, Lynn A.
Publicado no eNeuro (2017)

Endocannabinoid-Specific Impairment in Synaptic Plasticity in Striatum of Huntington's Disease Mouse Model

Por Sepers, Marja D., Smith-Dijak, Amy, LeDue, Jeff, Kolodziejczyk, Karolina, Mackie, Ken, Raymond, Lynn A.
Publicado no J Neurosci (2018)

NMDA receptor desensitization regulated by direct binding to PDZ1-2 domains of PSD-95

Por Sornarajah, Lavan, Vasuta, Oana Cristina, Zhang, Lily, Sutton, Christine, Li, Bo, El-Husseini, Alaa, Raymond, Lynn A.
Publicado em 2008

Real-time imaging of glutamate clearance reveals normal striatal uptake in Huntington disease mouse models

Por Parsons, Matthew P., Vanni, Matthieu P., Woodard, Cameron L., Kang, Rujun, Murphy, Timothy H., Raymond, Lynn A.
Publicado no Nat Commun (2016)

Altering cortical input unmasks synaptic phenotypes in the YAC128 cortico-striatal co-culture model of Huntington disease

Por Schmidt, Mandi E., Buren, Caodu, Mackay, James P., Cheung, Daphne, Dal Cengio, Louisa, Raymond, Lynn A., Hayden, Michael R.
Publicado no BMC Biol (2018)

Calpain and STriatal-Enriched protein tyrosine Phosphatase (STEP) activation contribute to extrasynaptic NMDA receptor localization in a Huntington's disease mouse model

Por Gladding, Clare M., Sepers, Marja D., Xu, Jian, Zhang, Lily Y.J., Milnerwood, Austen J., Lombroso, Paul J., Raymond, Lynn A.
Publicado em 2012

Bidirectional Control of Postsynaptic Density-95 (PSD-95) Clustering by Huntingtin

Por Parsons, Matthew P., Kang, Rujun, Buren, Caodu, Dau, Alejandro, Southwell, Amber L., Doty, Crystal N., Sanders, Shaun S., Hayden, Michael R., Raymond, Lynn A.
Publicado em 2014

Alterations in Striatal-Enriched Protein Tyrosine Phosphatase (STEP) Expression, Activation and Downstream Signaling in Early and Late Stages of the YAC128 Huntington’s Disease Mou...

Por Gladding, Clare M., Fan, Jing, Zhang, Lily Y. J., Wang, Liang, Xu, Jian, Li, Edward H. Y., Lombroso, Paul J., Raymond, Lynn A.
Publicado em 2014

Motor onset and diagnosis in Huntington disease using the diagnostic confidence level

Por Liu, Dawei, Long, Jeffrey D., Zhang, Ying, Raymond, Lynn A., Marder, Karen, Rosser, Anne, McCusker, Elizabeth A., Mills, James A., Paulsen, Jane S.
Publicado no J Neurol (2015)

Memory and synaptic deficits in Hip14/DHHC17 knockout mice

Por Milnerwood, Austen J., Parsons, Matthew P., Young, Fiona B., Singaraja, Roshni R., Franciosi, Sonia, Volta, Mattia, Bergeron, Sabrina, Hayden, Michael R., Raymond, Lynn A.
Publicado em 2013

Sudden death due to paralysis and synaptic and behavioral deficits when Hip14/Zdhhc17 is deleted in adult mice

Por Sanders, Shaun S., Parsons, Matthew P., Mui, Katherine K. N., Southwell, Amber L., Franciosi, Sonia, Cheung, Daphne, Waltl, Sabine, Raymond, Lynn A., Hayden, Michael R.
Publicado no BMC Biol (2016)

Refining the diagnosis of Huntington disease: the PREDICT-HD study

Por Biglan, Kevin M., Zhang, Ying, Long, Jeffrey D., Geschwind, Michael, Kang, Gail A., Killoran, Annie, Lu, Wenjing, McCusker, Elizabeth, Mills, James A., Raymond, Lynn A., Testa, Claudia, Wojcieszek, Joanne, Paulsen, Jane S.
Publicado em 2013

Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death

Por Divakaruni, Ajit S., Wallace, Martina, Buren, Caodu, Martyniuk, Kelly, Andreyev, Alexander Y., Li, Edward, Fields, Jerel A., Cordes, Thekla, Reynolds, Ian J., Bloodgood, Brenda L., Raymond, Lynn A., Metallo, Christian M., Murphy, Anne N.
Publicado no J Cell Biol (2017)

Cleavage at the 586 Amino Acid Caspase-6 Site in Mutant huntingtin Influences Caspase-6 Activation In Vivo

Por Graham, Rona K., Deng, Yu, Carroll, Jeffery, Vaid, Kuljeet, Cowan, Catherine, Pouladi, Mahmoud A., Metzler, Martina, Bissada, Nagat, Wang, Lili, Faull, Richard L. M., Gray, Michelle, Yang, X. William, Raymond, Lynn A., Hayden, Michael R.
Publicado em 2010