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An Automated Home-Cage System to Assess Learning and Performance of a Skilled Motor Task in a Mouse Model of Huntington’s Disease

Behavioral testing is a critical step in assessing the validity of rodent models of neurodegenerative disease, as well as evaluating the efficacy of pharmacological interventions. In models of Huntington’s disease (HD), a gradual progression of impairments is observed across ages, increasing the nee...

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Dettagli Bibliografici
Pubblicato in:eNeuro
Autori principali: Woodard, Cameron L., Bolaños, Federico, Boyd, James D., Silasi, Gergely, Murphy, Timothy H., Raymond, Lynn A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602104/
https://ncbi.nlm.nih.gov/pubmed/28929129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0141-17.2017
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