Stroma-derived HGF drives metabolic adaptation of colorectal cancer to angiogenesis inhibitors

Por Mira, Alessia, Morello, Virginia, Céspedes, Maria Virtudes, Perera, Timothy, Comoglio, Paolo M., Mangues, Ramon, Michieli, Paolo
Publicado no Oncotarget (2017)

Truncated RAF kinases drive resistance to MET inhibition in MET-addicted cancer cells

Por Petti, Consalvo, Picco, Gabriele, Martelli, Maria Luisa, Trisolini, Elena, Bucci, Enrico, Perera, Timothy, Isella, Claudio, Medico, Enzo
Publicado no Oncotarget (2014)

Heat-shock protein 27 (HSP27, HSPB1) is up-regulated by MET kinase inhibitors and confers resistance to MET-targeted therapy

Por Musiani, Daniele, Konda, John David, Pavan, Simona, Torchiaro, Erica, Sassi, Francesco, Noghero, Alessio, Erriquez, Jessica, Perera, Timothy, Olivero, Martina, Di Renzo, Maria Flavia
Publicado no FASEB J (2014)

Tyrosine Phosphorylation of Tau by the Src Family Kinases Lck and Fyn

Por Bird Ian N, Price Caroline, Ward Malcolm A, Byers Helen L, Leung Kit-Yi, Derkinderen Pascal, Scales Timothy ME, Perera Timothy, Kellie Stuart, Williamson Ritchie, Anderton Brian H, Reynolds C Hugh
Publicado em 2011-01-01

Tyrosine Phosphorylation of Tau by the Src Family Kinases Lck and Fyn

Por Scales, Timothy ME, Derkinderen, Pascal, Leung, Kit-Yi, Byers, Helen L, Ward, Malcolm A, Price, Caroline, Bird, Ian N, Perera, Timothy, Kellie, Stuart, Williamson, Ritchie, Anderton, Brian H, Reynolds, C Hugh
Publicado em 2011

C-met inhibition blocks bone metastasis development induced by renal cancer stem cells

Por D'Amico, Lucia, Belisario, Dimas, Migliardi, Giorgia, Grange, Cristina, Bussolati, Benedetta, D'Amelio, Patrizia, Perera, Timothy, Dalmasso, Ettore, Carbonare, Luca Dalle, Godio, Laura, Comoglio, Paolo, Trusolino, Livio, Ferracini, Riccardo, Roato, Ilaria
Publicado no Oncotarget (2016)

MET inhibition overcomes radiation resistance of glioblastoma stem‐like cells

Por De Bacco, Francesca, D'Ambrosio, Antonio, Casanova, Elena, Orzan, Francesca, Neggia, Roberta, Albano, Raffaella, Verginelli, Federica, Cominelli, Manuela, Poliani, Pietro L, Luraghi, Paolo, Reato, Gigliola, Pellegatta, Serena, Finocchiaro, Gaetano, Perera, Timothy, Garibaldi, Elisabetta, Gabriele, Pietro, Comoglio, Paolo M, Boccaccio, Carla
Publicado no EMBO Mol Med (2016)

The phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation

Por Vivanco, Igor, Rohle, Daniel, Versele, Matthias, Iwanami, Akio, Kuga, Daisuke, Oldrini, Barbara, Tanaka, Kazuhiro, Dang, Julie, Kubek, Sara, Palaskas, Nicolaos, Hsueh, Teli, Evans, Michael, Mulholland, David, Wolle, Daniel, Rajasekaran, Sigrid, Rajasekaran, Ayyappan, Liau, Linda M., Cloughesy, Timothy F., Dikic, Ivan, Brennan, Cameron, Wu, Hong, Mischel, Paul S., Perera, Timothy, Mellinghoff, Ingo K.
Publicado em 2010

Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer

Por Bardelli, Alberto, Corso, Simona, Bertotti, Andrea, Hobor, Sebastijan, Valtorta, Emanuele, Siravegna, Giulia, Sartore-Bianchi, Andrea, Scala, Elisa, Cassingena, Andrea, Zecchin, Davide, Apicella, Maria, Migliardi, Giorgia, Galimi, Francesco, Lauricella, Calogero, Zanon, Carlo, Perera, Timothy, Veronese, Silvio, Corti, Giorgio, Amatu, Alessio, Gambacorta, Marcello, Diaz, Luis A., Sausen, Mark, Velculescu, Victor E., Comoglio, Paolo, Trusolino, Livio, Di Nicolantonio, Federica, Giordano, Silvia, Siena, Salvatore
Publicado em 2013