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Tyrosine Phosphorylation of Tau by the Src Family Kinases Lck and Fyn

BACKGROUND: Tau protein is the principal component of the neurofibrillary tangles found in Alzheimer's disease, where it is hyperphosphorylated on serine and threonine residues, and recently phosphotyrosine has been demonstrated. The Src-family kinase Fyn has been linked circumstantially to the...

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Bibliographic Details
Main Authors: Scales, Timothy ME, Derkinderen, Pascal, Leung, Kit-Yi, Byers, Helen L, Ward, Malcolm A, Price, Caroline, Bird, Ian N, Perera, Timothy, Kellie, Stuart, Williamson, Ritchie, Anderton, Brian H, Reynolds, C Hugh
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037338/
https://ncbi.nlm.nih.gov/pubmed/21269457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-12
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