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Tyrosine 394 Is Phosphorylated in Alzheimer's Paired Helical Filament Tau and in Fetal Tau with c-Abl as the Candidate Tyrosine Kinase

Tau is a major microtubule-associated protein of axons and is also the principal component of the paired helical filaments (PHFs) that comprise the neurofibrillary tangles found in Alzheimer's disease and other tauopathies. Besides phosphorylation of tau on serine and threonine residues in both...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Derkinderen, Pascal, Scales, Timothy M. E., Hanger, Diane P., Leung, Kit-Yi, Byers, Helen L., Ward, Malcolm A., Lenz, Christof, Price, Caroline, Bird, Ian N., Perera, Timothy, Kellie, Stuart, Williamson, Ritchie, Noble, Wendy, Van Etten, Richard A., Leroy, Karelle, Brion, Jean-Pierre, Reynolds, C. Hugh, Anderton, Brian H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2005
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725430/
https://ncbi.nlm.nih.gov/pubmed/16014719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1487-05.2005
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