MET inhibition overcomes radiation resistance of glioblastoma stem‐like cells

Glioblastoma (GBM) contains stem‐like cells (GSCs) known to be resistant to ionizing radiation and thus responsible for therapeutic failure and rapidly lethal tumor recurrence. It is known that GSC radioresistance relies on efficient activation of the DNA damage response, but the mechanisms linking...

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Bibliographic Details
Published in:EMBO Mol Med
Main Authors: De Bacco, Francesca, D'Ambrosio, Antonio, Casanova, Elena, Orzan, Francesca, Neggia, Roberta, Albano, Raffaella, Verginelli, Federica, Cominelli, Manuela, Poliani, Pietro L, Luraghi, Paolo, Reato, Gigliola, Pellegatta, Serena, Finocchiaro, Gaetano, Perera, Timothy, Garibaldi, Elisabetta, Gabriele, Pietro, Comoglio, Paolo M, Boccaccio, Carla
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130292/
https://ncbi.nlm.nih.gov/pubmed/27138567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505890
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