Intra-tumoral dendritic cells increase efficacy of peripheral vaccination by modulation of glioma microenvironment

Pilot data showed that adding intratumoral (IT) injection of dendritic cells (DCs) prolongs survival of patients affected by glioblastoma multiforme (GBM) treated by subcutaneous (SC) delivery of DCs. Using a murine model resembling GBM, we investigated the immunological mechanisms underlying this e...

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Библиографические подробности
Главные авторы: Pellegatta, Serena, Poliani, Pietro Luigi, Stucchi, Elena, Corno, Daniela, Colombo, Chiara Agnese, Orzan, Francesca, Ravanini, Maria, Finocchiaro, Gaetano
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2010
Предметы:
Basic and Translational Investigations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940598/
https://ncbi.nlm.nih.gov/pubmed/20308315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop024
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