Intra-tumoral dendritic cells increase efficacy of peripheral vaccination by modulation of glioma microenvironment

Pilot data showed that adding intratumoral (IT) injection of dendritic cells (DCs) prolongs survival of patients affected by glioblastoma multiforme (GBM) treated by subcutaneous (SC) delivery of DCs. Using a murine model resembling GBM, we investigated the immunological mechanisms underlying this e...

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Detalhes bibliográficos
Main Authors: Pellegatta, Serena, Poliani, Pietro Luigi, Stucchi, Elena, Corno, Daniela, Colombo, Chiara Agnese, Orzan, Francesca, Ravanini, Maria, Finocchiaro, Gaetano
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940598/
https://ncbi.nlm.nih.gov/pubmed/20308315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop024
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