Intra-tumoral dendritic cells increase efficacy of peripheral vaccination by modulation of glioma microenvironment

Pilot data showed that adding intratumoral (IT) injection of dendritic cells (DCs) prolongs survival of patients affected by glioblastoma multiforme (GBM) treated by subcutaneous (SC) delivery of DCs. Using a murine model resembling GBM, we investigated the immunological mechanisms underlying this e...

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Autori principali: Pellegatta, Serena, Poliani, Pietro Luigi, Stucchi, Elena, Corno, Daniela, Colombo, Chiara Agnese, Orzan, Francesca, Ravanini, Maria, Finocchiaro, Gaetano
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
Soggetti:
Basic and Translational Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940598/
https://ncbi.nlm.nih.gov/pubmed/20308315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop024
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