Human Peripheral Lymphoid Tissues Contain Autoimmune Regulator-Expressing Dendritic Cells

Autoimmune regulator (AIRE) modulates the expression of tissue-restricted antigens (TSAs) and promotes central tolerance in the thymus. However, few autoreactive T cells escape negative selection and reach the periphery, where peripheral tolerance is required to avoid autoimmunity. Murine lymph node...

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Bibliographic Details
Main Authors: Poliani, Pietro Luigi, Kisand, Kai, Marrella, Veronica, Ravanini, Maria, Notarangelo, Luigi Daniele, Villa, Anna, Peterson, Pärt, Facchetti, Fabio
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2010
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Short Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832133/
https://ncbi.nlm.nih.gov/pubmed/20093495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090956
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