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Human Peripheral Lymphoid Tissues Contain Autoimmune Regulator-Expressing Dendritic Cells
Autoimmune regulator (AIRE) modulates the expression of tissue-restricted antigens (TSAs) and promotes central tolerance in the thymus. However, few autoreactive T cells escape negative selection and reach the periphery, where peripheral tolerance is required to avoid autoimmunity. Murine lymph node...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Investigative Pathology
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832133/ https://ncbi.nlm.nih.gov/pubmed/20093495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090956 |
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