Intra-tumoral dendritic cells increase efficacy of peripheral vaccination by modulation of glioma microenvironment

Pilot data showed that adding intratumoral (IT) injection of dendritic cells (DCs) prolongs survival of patients affected by glioblastoma multiforme (GBM) treated by subcutaneous (SC) delivery of DCs. Using a murine model resembling GBM, we investigated the immunological mechanisms underlying this e...

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Hlavní autoři: Pellegatta, Serena, Poliani, Pietro Luigi, Stucchi, Elena, Corno, Daniela, Colombo, Chiara Agnese, Orzan, Francesca, Ravanini, Maria, Finocchiaro, Gaetano
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940598/
https://ncbi.nlm.nih.gov/pubmed/20308315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop024
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