Clonal evolution and KRAS-MET coamplification during secondary resistance to EGFR-targeted therapy in metastatic colorectal cancer

Por Sartore-Bianchi, Andrea, Valtorta, Emanuele, Amatu, Alessio, Veronese, Silvio, Lauricella, Calogero, Bonazzina, Erica, Siravegna, Giulia, Truini, Mauro, Bardelli, Alberto, Siena, Salvatore
Publicado no ESMO Open (2016)

Enteric-type adenocarcinoma of the lung harbouring a novel KRAS Q22K mutation with concomitant KRAS polysomy: a case report

Por Metro, Giulio, Valtorta, Emanuele, Siggillino, Annamaria, Lauricella, Calogero, Cenci, Matteo, Ludovini, Vienna, Minenza, Elisa, Prosperi, Enrico, Ricciuti, Biagio, Rebonato, Alberto, Bassetti, Alessandra, Crinò, Lucio
Publicado no Ecancermedicalscience (2015)

KRAS mutations affect prognosis of non-small-cell lung cancer patients treated with first-line platinum containing chemotherapy

Por Marabese, Mirko, Ganzinelli, Monica, Garassino, Marina C., Shepherd, Frances A., Piva, Sheila, Caiola, Elisa, Macerelli, Marianna, Bettini, Anna, Lauricella, Calogero, Floriani, Irene, Farina, Gabriella, Longo, Flavia, Bonomi, Lucia, Fabbri, M. Agnese, Veronese, Silvio, Marsoni, Silvia, Broggini, Massimo, Rulli, Eliana
Publicado no Oncotarget (2015)

Novel CAD-ALK gene rearrangement is drugable by entrectinib in colorectal cancer

Por Amatu, Alessio, Somaschini, Alessio, Cerea, Giulio, Bosotti, Roberta, Valtorta, Emanuele, Buonandi, Pasquale, Marrapese, Giovanna, Veronese, Silvio, Luo, David, Hornby, Zachary, Multani, Pratik, Murphy, Danielle, Shoemaker, Robert, Lauricella, Calogero, Giannetta, Laura, Maiolani, Martina, Vanzulli, Angelo, Ardini, Elena, Galvani, Arturo, Isacchi, Antonella, Sartore-Bianchi, Andrea, Siena, Salvatore
Publicado no Br J Cancer (2015)

Multi-Center Evaluation of the Fully Automated PCR-Based Idylla(™) KRAS Mutation Assay for Rapid KRAS Mutation Status Determination on Formalin-Fixed Paraffin-Embedded Tissue of Hu...

Por Solassol, Jérôme, Vendrell, Julie, Märkl, Bruno, Haas, Christian, Bellosillo, Beatriz, Montagut, Clara, Smith, Matthew, O’Sullivan, Brendan, D’Haene, Nicky, Le Mercier, Marie, Grauslund, Morten, Melchior, Linea Cecilie, Burt, Emma, Cotter, Finbarr, Stieber, Daniel, Schmitt, Fernando de Lander, Motta, Valentina, Lauricella, Calogero, Colling, Richard, Soilleux, Elizabeth, Fassan, Matteo, Mescoli, Claudia, Collin, Christine, Pagès, Jean-Christophe, Sillekens, Peter
Publicado no PLoS One (2016)

Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer

Por Bardelli, Alberto, Corso, Simona, Bertotti, Andrea, Hobor, Sebastijan, Valtorta, Emanuele, Siravegna, Giulia, Sartore-Bianchi, Andrea, Scala, Elisa, Cassingena, Andrea, Zecchin, Davide, Apicella, Maria, Migliardi, Giorgia, Galimi, Francesco, Lauricella, Calogero, Zanon, Carlo, Perera, Timothy, Veronese, Silvio, Corti, Giorgio, Amatu, Alessio, Gambacorta, Marcello, Diaz, Luis A., Sausen, Mark, Velculescu, Victor E., Comoglio, Paolo, Trusolino, Livio, Di Nicolantonio, Federica, Giordano, Silvia, Siena, Salvatore
Publicado em 2013

Monitoring clonal evolution and resistance to EGFR blockade in the blood of metastatic colorectal cancer patients

Por Siravegna, Giulia, Mussolin, Benedetta, Buscarino, Michela, Corti, Giorgio, Cassingena, Andrea, Crisafulli, Giovanni, Ponzetti, Agostino, Cremolini, Chiara, Amatu, Alessio, Lauricella, Calogero, Lamba, Simona, Hobor, Sebastijan, Avallone, Antonio, Valtorta, Emanuele, Rospo, Giuseppe, Medico, Enzo, Motta, Valentina, Antoniotti, Carlotta, Tatangelo, Fabiana, Bellosillo, Beatriz, Veronese, Silvio, Budillon, Alfredo, Montagut, Clara, Racca, Patrizia, Marsoni, Silvia, Falcone, Alfredo, Corcoran, Ryan B., Di Nicolantonio, Federica, Loupakis, Fotios, Siena, Salvatore, Sartore-Bianchi, Andrea, Bardelli, Alberto
Publicado no Nat Med (2015)

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

Por Bettegowda, Chetan, Sausen, Mark, Leary, Rebecca J., Kinde, Isaac, Wang, Yuxuan, Agrawal, Nishant, Bartlett, Bjarne R., Wang, Hao, Luber, Brandon, Alani, Rhoda M., Antonarakis, Emmanuel S., Azad, Nilofer S., Bardelli, Alberto, Brem, Henry, Cameron, John L., Lee, Clarence C., Fecher, Leslie A., Gallia, Gary L., Gibbs, Peter, Le, Dung, Giuntoli, Robert L., Goggins, Michael, Hogarty, Michael D., Holdhoff, Matthias, Hong, Seung-Mo, Jiao, Yuchen, Juhl, Hartmut H., Kim, Jenny J., Siravegna, Giulia, Laheru, Daniel A., Lauricella, Calogero, Lim, Michael, Lipson, Evan J., Marie, Suely Kazue Nagahashi, Netto, George J., Oliner, Kelly S., Olivi, Alessandro, Olsson, Louise, Riggins, Gregory J., Sartore-Bianchi, Andrea, Schmidt, Kerstin, Shih, le-Ming, Oba-Shinjo, Sueli Mieko, Siena, Salvatore, Theodorescu, Dan, Tie, Jeanne, Harkins, Timothy T., Veronese, Silvio, Wang, Tian-Li, Weingart, Jon D., Wolfgang, Christopher L., Wood, Laura D., Xing, Dongmei, Hruban, Ralph H., Wu, Jian, Allen, Peter J., Schmidt, C. Max, Choti, Michael A., Velculescu, Victor E., Kinzler, Kenneth W., Vogelstein, Bert, Papadopoulos, Nickolas, Diaz, Luis A.
Publicado em 2014