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Novel CAD-ALK gene rearrangement is drugable by entrectinib in colorectal cancer
BACKGROUND: Activated anaplastic lymphoma kinase (ALK) gene fusions are recurrent events in a small fraction of colorectal cancers (CRCs), although these events have not yet been exploited as in other malignancies. METHODS: We detected ALK protein expression by immunohistochemistry and gene rearrang...
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| Publicado no: | Br J Cancer |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4701996/ https://ncbi.nlm.nih.gov/pubmed/26633560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.401 |
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