Streptococcus pneumoniae DNA Gyrase and Topoisomerase IV: Overexpression, Purification, and Differential Inhibition by Fluoroquinolones

Por Pan, Xiao-Su, Fisher, L. Mark
Publicado em 1999

DNA Gyrase and Topoisomerase IV Are Dual Targets of Clinafloxacin Action in Streptococcus pneumoniae

Por Pan, Xiao-Su, Fisher, L. Mark
Publicado em 1998

Quinolone Resistance Mutations in Streptococcus pneumoniae GyrA and ParC Proteins: Mechanistic Insights into Quinolone Action from Enzymatic Analysis, Intracellular Levels, and Ph...

Por Pan, Xiao-Su, Yague, Genoveva, Fisher, L. Mark
Publicado em 2001

Functional determinants of gate-DNA selection and cleavage by bacterial type II topoisomerases

Por Arnoldi, Elisa, Pan, Xiao-Su, Fisher, L Mark
Publicado em 2013

Grepafloxacin, a Dimethyl Derivative of Ciprofloxacin, Acts Preferentially through Gyrase in Streptococcus pneumoniae: Role of the C-5 Group in Target Specificity

Por Morris, Julia E., Pan, Xiao-Su, Fisher, L. Mark
Publicado em 2002

Probing the Differential Interactions of Quinazolinedione PD 0305970 and Quinolones with Gyrase and Topoisomerase IV

Por Pan, Xiao-Su, Gould, Katherine A., Fisher, L. Mark
Publicado em 2009

Clerocidin selectively modifies the gyrase-DNA gate to induce irreversible and reversible DNA damage

Por Pan, Xiao Su, Dias, Miriam, Palumbo, Manlio, Fisher, L. Mark
Publicado em 2008

Mycobacterium tuberculosis DNA Gyrase: Interaction with Quinolones and Correlation with Antimycobacterial Drug Activity

Por Aubry, Alexandra, Pan, Xiao-Su, Fisher, L. Mark, Jarlier, Vincent, Cambau, Emmanuelle
Publicado em 2004

Ciprofloxacin Dimers Target Gyrase in Streptococcus pneumoniae

Por Gould, Katherine A., Pan, Xiao-Su, Kerns, Robert J., Fisher, L. Mark
Publicado em 2004

Cleavable-Complex Formation by Wild-Type and Quinolone-Resistant Streptococcus pneumoniae Type II Topoisomerases Mediated by Gemifloxacin and Other Fluoroquinolones

Por Yague, Genoveva, Morris, Julia E., Pan, Xiao-Su, Gould, Katherine A., Fisher, L. Mark
Publicado em 2002

Engineering the Specificity of Antibacterial Fluoroquinolones: Benzenesulfonamide Modifications at C-7 of Ciprofloxacin Change Its Primary Target in Streptococcus pneumoniae from...

Por Alovero, Fabiana L., Pan, Xiao-Su, Morris, Julia E., Manzo, Ruben H., Fisher, L. Mark
Publicado em 2000

The Difficult Case of Crystallization and Structure Solution for the ParC55 Breakage-Reunion Domain of Topoisomerase IV from Streptococcus pneumoniae

Por Sohi, Maninder K., Veselkov, Dennis A., Laponogov, Ivan, Pan, Xiao-Su, Fisher, L. Mark, Sanderson, Mark R.
Publicado em 2008

Structure of an ‘open’ clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport

Por Laponogov, Ivan, Veselkov, Dennis A., Crevel, Isabelle M.-T., Pan, Xiao-Su, Fisher, L. Mark, Sanderson, Mark R.
Publicado em 2013

Small-Colony Mutants of Staphylococcus aureus Allow Selection of Gyrase-Mediated Resistance to Dual-Target Fluoroquinolones

Por Pan, Xiao-Su, Hamlyn, Penelope J., Talens-Visconti, Raquel, Alovero, Fabiana L., Manzo, Ruben H., Fisher, L. Mark
Publicado em 2002

Correction: Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases

Por Laponogov, Ivan, Pan, Xiao-Su, Veselkov, Dennis A., McAuley, Katherine E., Fisher, L. Mark, Sanderson, Mark R.
Publicado em 2010

Correction: Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases

Por Laponogov, Ivan, Pan, Xiao-Su, Veselkov, Dennis A., McAuley, Katherine E., Fisher, L. Mark, Sanderson, Mark R.
Publicado em 2010

Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases

Por Laponogov, Ivan, Pan, Xiao-Su, Veselkov, Dennis A., McAuley, Katherine E., Fisher, L. Mark, Sanderson, Mark R.
Publicado em 2010

Exploring the active site of the Streptococcus pneumoniae topoisomerase IV–DNA cleavage complex with novel 7,8-bridged fluoroquinolones

Por Laponogov, Ivan, Pan, Xiao-Su, Veselkov, Dennis A., Cirz, Ryan T., Wagman, Allan, Moser, Heinz E., Fisher, L. Mark, Sanderson, Mark R.
Publicado no Open Biol (2016)

Breakage-Reunion Domain of Streptococcus pneumoniae Topoisomerase IV: Crystal Structure of a Gram-Positive Quinolone Target

Por Laponogov, Ivan, Veselkov, Dennis A., Sohi, Maninder K., Pan, Xiao-Su, Achari, Aniruddha, Yang, Cheng, Ferrara, Joseph D., Fisher, L. Mark, Sanderson, Mark R.
Publicado em 2007

Structure of a quinolone-stabilized cleavage complex of topoisomerase IV from Klebsiella pneumoniae and comparison with a related Streptococcus pneumoniae complex

Por Veselkov, Dennis A., Laponogov, Ivan, Pan, Xiao-Su, Selvarajah, Jogitha, Skamrova, Galyna B., Branstrom, Arthur, Narasimhan, Jana, Prasad, Josyula V. N. Vara, Fisher, L. Mark, Sanderson, Mark R.
Publicado no Acta Crystallogr D Struct Biol (2016)