Exploring the active site of the Streptococcus pneumoniae topoisomerase IV–DNA cleavage complex with novel 7,8-bridged fluoroquinolones

Eitemau Tebyg

• Structure of a quinolone-stabilized cleavage complex of topoisomerase IV from Klebsiella pneumoniae and comparison with a related Streptococcus pneumoniae complex
  gan: Veselkov, Dennis A., et al.
  Cyhoeddwyd: (2016)
• The Difficult Case of Crystallization and Structure Solution for the ParC55 Breakage-Reunion Domain of Topoisomerase IV from Streptococcus pneumoniae
  gan: Sohi, Maninder K., et al.
  Cyhoeddwyd: (2008)
• Breakage-Reunion Domain of Streptococcus pneumoniae Topoisomerase IV: Crystal Structure of a Gram-Positive Quinolone Target
  gan: Laponogov, Ivan, et al.
  Cyhoeddwyd: (2007)
• Streptococcus pneumoniae DNA Gyrase and Topoisomerase IV: Overexpression, Purification, and Differential Inhibition by Fluoroquinolones
  gan: Pan, Xiao-Su, et al.
  Cyhoeddwyd: (1999)
• Clerocidin interacts with the cleavage complex of Streptococcus pneumoniae topoisomerase IV to induce selective irreversible DNA damage
  gan: Richter, Sara N., et al.
  Cyhoeddwyd: (2006)