Clerocidin interacts with the cleavage complex of Streptococcus pneumoniae topoisomerase IV to induce selective irreversible DNA damage

Lignende værker

• The topoisomerase II poison clerocidin alkylates non-paired guanines of DNA: implications for irreversible stimulation of DNA cleavage
  af: Gatto, Barbara, et al.
  Udgivet: (2001)
• Clerocidin selectively modifies the gyrase-DNA gate to induce irreversible and reversible DNA damage
  af: Pan, Xiao Su, et al.
  Udgivet: (2008)
• Hot-spot consensus of fluoroquinolone-mediated DNA cleavage by Gram-negative and Gram-positive type II DNA topoisomerases
  af: Richter, Sara N., et al.
  Udgivet: (2007)
• Involvement of topoisomerase IV and DNA gyrase as ciprofloxacin targets in Streptococcus pneumoniae.
  af: Pan, X S, et al.
  Udgivet: (1996)
• Exploring the active site of the Streptococcus pneumoniae topoisomerase IV–DNA cleavage complex with novel 7,8-bridged fluoroquinolones
  af: Laponogov, Ivan, et al.
  Udgivet: (2016)