Loading...

Quinolone Resistance Mutations in Streptococcus pneumoniae GyrA and ParC Proteins: Mechanistic Insights into Quinolone Action from Enzymatic Analysis, Intracellular Levels, and Phenotypes of Wild-Type and Mutant Proteins

Mutations in DNA gyrase and/or topoisomerase IV genes are frequently encountered in quinolone-resistant mutants of Streptococcus pneumoniae. To investigate the mechanism of their effects at the molecular and cellular levels, we have used an Escherichia coli system to overexpress S. pneumoniae gyrase...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Pan, Xiao-Su, Yague, Genoveva, Fisher, L. Mark
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90795/
https://ncbi.nlm.nih.gov/pubmed/11600369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.11.3140-3147.2001
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!