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Cleavable-Complex Formation by Wild-Type and Quinolone-Resistant Streptococcus pneumoniae Type II Topoisomerases Mediated by Gemifloxacin and Other Fluoroquinolones

Gemifloxacin is a recently developed fluoroquinolone with potent activity against Streptococcus pneumoniae. We show that the drug is more active than moxifloxacin, gatifloxacin, levofloxacin, and ciprofloxacin against S. pneumoniae strain 7785 (MICs, 0.03 to 0.06 μg/ml versus 0.25, 0.25, 1, and 1 to...

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Bibliografische gegevens
Hoofdauteurs: Yague, Genoveva, Morris, Julia E., Pan, Xiao-Su, Gould, Katherine A., Fisher, L. Mark
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2002
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC127068/
https://ncbi.nlm.nih.gov/pubmed/11796351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.2.413-419.2002
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