Cleavable-Complex Formation by Wild-Type and Quinolone-Resistant Streptococcus pneumoniae Type II Topoisomerases Mediated by Gemifloxacin and Other Fluoroquinolones

Gemifloxacin is a recently developed fluoroquinolone with potent activity against Streptococcus pneumoniae. We show that the drug is more active than moxifloxacin, gatifloxacin, levofloxacin, and ciprofloxacin against S. pneumoniae strain 7785 (MICs, 0.03 to 0.06 μg/ml versus 0.25, 0.25, 1, and 1 to...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yague, Genoveva, Morris, Julia E., Pan, Xiao-Su, Gould, Katherine A., Fisher, L. Mark
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2002
Pynciau:
Mechanisms of Resistance
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC127068/
https://ncbi.nlm.nih.gov/pubmed/11796351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.2.413-419.2002
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