Mycobacterium tuberculosis DNA Gyrase: Interaction with Quinolones and Correlation with Antimycobacterial Drug Activity

Genome studies suggest that DNA gyrase is the sole type II topoisomerase and likely the unique target of quinolones in Mycobacterium tuberculosis. Despite the emerging importance of quinolones in the treatment of mycobacterial disease, the slow growth and high pathogenicity of M. tuberculosis have p...

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Bibliografiska uppgifter
Huvudupphovsmän: Aubry, Alexandra, Pan, Xiao-Su, Fisher, L. Mark, Jarlier, Vincent, Cambau, Emmanuelle
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2004
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Mechanisms of Action: Physiological Effects
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC375300/
https://ncbi.nlm.nih.gov/pubmed/15047530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1281-1288.2004
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