Mycobacterium tuberculosis DNA Gyrase: Interaction with Quinolones and Correlation with Antimycobacterial Drug Activity

Genome studies suggest that DNA gyrase is the sole type II topoisomerase and likely the unique target of quinolones in Mycobacterium tuberculosis. Despite the emerging importance of quinolones in the treatment of mycobacterial disease, the slow growth and high pathogenicity of M. tuberculosis have p...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Aubry, Alexandra, Pan, Xiao-Su, Fisher, L. Mark, Jarlier, Vincent, Cambau, Emmanuelle
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2004
Konular:
Mechanisms of Action: Physiological Effects
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC375300/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15047530/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.4.1281-1288.2004
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