Mycobacterium tuberculosis DNA Gyrase: Interaction with Quinolones and Correlation with Antimycobacterial Drug Activity

Genome studies suggest that DNA gyrase is the sole type II topoisomerase and likely the unique target of quinolones in Mycobacterium tuberculosis. Despite the emerging importance of quinolones in the treatment of mycobacterial disease, the slow growth and high pathogenicity of M. tuberculosis have p...

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Argitaratua izan da:	Antimicrob Agents Chemother
Egile Nagusiak:	Aubry, Alexandra, Pan, Xiao-Su, Fisher, L. Mark, Jarlier, Vincent, Cambau, Emmanuelle
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 2004
Gaiak:	Mechanisms of Action: Physiological Effects
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC375300/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15047530/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.4.1281-1288.2004
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