Mycobacterium tuberculosis DNA Gyrase: Interaction with Quinolones and Correlation with Antimycobacterial Drug Activity

Genome studies suggest that DNA gyrase is the sole type II topoisomerase and likely the unique target of quinolones in Mycobacterium tuberculosis. Despite the emerging importance of quinolones in the treatment of mycobacterial disease, the slow growth and high pathogenicity of M. tuberculosis have p...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Autores principales:	Aubry, Alexandra, Pan, Xiao-Su, Fisher, L. Mark, Jarlier, Vincent, Cambau, Emmanuelle
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2004
Materias:	Mechanisms of Action: Physiological Effects
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC375300/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15047530/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.4.1281-1288.2004
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