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Mycobacterium tuberculosis DNA Gyrase: Interaction with Quinolones and Correlation with Antimycobacterial Drug Activity

Genome studies suggest that DNA gyrase is the sole type II topoisomerase and likely the unique target of quinolones in Mycobacterium tuberculosis. Despite the emerging importance of quinolones in the treatment of mycobacterial disease, the slow growth and high pathogenicity of M. tuberculosis have p...

詳細記述

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書誌詳細
主要な著者: Aubry, Alexandra, Pan, Xiao-Su, Fisher, L. Mark, Jarlier, Vincent, Cambau, Emmanuelle
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC375300/
https://ncbi.nlm.nih.gov/pubmed/15047530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1281-1288.2004
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