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Mycobacterium tuberculosis DNA Gyrase: Interaction with Quinolones and Correlation with Antimycobacterial Drug Activity
Genome studies suggest that DNA gyrase is the sole type II topoisomerase and likely the unique target of quinolones in Mycobacterium tuberculosis. Despite the emerging importance of quinolones in the treatment of mycobacterial disease, the slow growth and high pathogenicity of M. tuberculosis have p...
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Main Authors: | , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
American Society for Microbiology
2004
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC375300/ https://ncbi.nlm.nih.gov/pubmed/15047530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1281-1288.2004 |
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