Helper virus-mediated downregulation of transgene expression permits production of recalcitrant helper-dependent adenoviral vector

by Palmer, Donna J, Grove, Nathan C, Ng, Philip
Published in Mol Ther Methods Clin Dev (2016)

Production of CRISPR/Cas9-Mediated Self-Cleaving Helper-Dependent Adenoviruses

by Palmer, Donna J., Turner, Dustin L., Ng, Philip
Published in Mol Ther Methods Clin Dev (2019)

Bi-allelic Homology-Directed Repair with Helper-Dependent Adenoviruses

by Palmer, Donna J., Turner, Dustin L., Ng, Philip
Published in Mol Ther Methods Clin Dev (2019)

A Single “All-in-One” Helper-Dependent Adenovirus to Deliver Donor DNA and CRISPR/Cas9 for Efficient Homology-Directed Repair

by Palmer, Donna J., Turner, Dustin L., Ng, Philip
Published in Mol Ther Methods Clin Dev (2020)

Gene Editing with Helper-Dependent Adenovirus Can Efficiently Introduce Multiple Changes Simultaneously over a Large Genomic Region

by Palmer, Donna J., Grove, Nathan C., Turner, Dustin L., Ng, Philip
Published in Mol Ther Nucleic Acids (2017)

Correction of Hyperbilirubinemia in Gunn Rats Using Clinically Relevant Low Doses of Helper-Dependent Adenoviral Vectors

by Dimmock, David, Brunetti-Pierri, Nicola, Palmer, Donna J., Beaudet, Arthur L., Ng, Philip
Published 2011

The Role of Endosomal Escape and Mitogen-Activated Protein Kinases in Adenoviral Activation of the Innate Immune Response

by Smith, Jeffrey S., Xu, Zhili, Tian, Jie, Palmer, Donna J., Ng, Philip, Byrnes, Andrew P.
Published 2011

Adenovirus–Retrovirus Hybrid Vectors Achieve Highly Enhanced Tumor Transduction and Antitumor Efficacy In Vivo

by Kubo, Shuji, Haga, Kazunori, Tamamoto, Atsuko, Palmer, Donna J, Ng, Philip, Okamura, Haruki, Kasahara, Noriyuki
Published 2011

Short-Term Rescue of Neonatal Lethality in a Mouse Model of Propionic Acidemia by Gene Therapy

by Hofherr, Sean E., Senac, Julien S., Chen, Christopher Y., Palmer, Donna J., Ng, Philip, Barry, Michael A.
Published 2009

Vasoactive Intestinal Peptide Increases Hepatic Transduction and Reduces Innate Immune Response Following Administration of Helper-dependent Ad

by Vetrini, Francesco, Brunetti-Pierri, Nicola, Palmer, Donna J, Bertin, Terry, Grove, Nathan C, Finegold, Milton J, Ng, Philip
Published 2010

Homology Requirements for Efficient, Footprintless Gene Editing at the CFTR Locus in Human iPSCs with Helper-dependent Adenoviral Vectors

by Palmer, Donna J, Grove, Nathan C, Ing, Jordan, Crane, Ana M, Venken, Koen, Davis, Brian R, Ng, Philip
Published in Mol Ther Nucleic Acids (2016)

Functional Prestin Transduction of Immature Outer Hair Cells from Normal and Prestin-Null Mice

by Xia, Anping, Wooltorton, Julian R.A., Palmer, Donna J., Ng, Philip, Pereira, Fred A., Eatock, Ruth Anne, Oghalai, John S.
Published 2008

Phenotypic Correction of Ornithine Transcarbamylase Deficiency Using Low Dose Helper Dependent Adenoviral Vectors

by Brunetti-Pierri, Nicola, Clarke, Christopher, Mane, Viraj, Palmer, Donna J., Lanpher, Brendan, Sun, Qin, O’Brien, William, Lee, Brendan
Published 2008

Differential Type I Interferon-dependent Transgene Silencing of Helper-dependent Adenoviral vs. Adeno-associated Viral Vectors In Vivo

by Suzuki, Masataka, Bertin, Terry K, Rogers, Geoffrey L, Cela, Racel G, Zolotukhin, Irene, Palmer, Donna J, Ng, Philip, Herzog, Roland W, Lee, Brendan
Published 2013

In Vivo Stable Transduction of Humanized Liver Tissue in Chimeric Mice via High-Capacity Adenovirus–Lentivirus Hybrid Vector

by Kubo, Shuji, Kataoka, Miho, Tateno, Chise, Yoshizato, Katsutoshi, Kawasaki, Yoshiko, Kimura, Takahiro, Faure-Kumar, Emmanuelle, Palmer, Donna J., Ng, Philip, Okamura, Haruki, Kasahara, Noriyuki
Published 2010

Conditional Disruption of Hepatic Carbamoyl Phosphate Synthetase 1 in Mice Results in Hyperammonemia without Orotic Aciduria and Can be Corrected by Liver-Directed Gene Therapy

by Khoja, Suhail, Nitzahn, Matt, Hermann, Kip, Truong, Brian, Borzone, Roberta, Willis, Brandon, Rudd, Mitchell, Palmer, Donna J., Ng, Philip, Brunetti-Pierri, Nicola, Lipshutz, Gerald S.
Published in Mol Genet Metab (2018)

Hepatic glutamine synthetase augmentation enhances ammonia detoxification.

by Soria, Leandro R., Nitzahn, Matthew, Angelis, Angela De, Khoja, Suhail, Attanasio, Sergio, Annunziata, Patrizia, Palmer, Donna J., Ng, Philip, Lipshutz, Gerald S., Brunetti-Pierri, Nicola
Published in J Inherit Metab Dis (2019)

Mapping axon initial segment structure and function by multiplexed proximity biotinylation

by Hamdan, Hamdan, Lim, Brian C., Torii, Tomohiro, Joshi, Abhijeet, Konning, Matthias, Smith, Cameron, Palmer, Donna J., Ng, Philip, Leterrier, Christophe, Oses-Prieto, Juan A., Burlingame, Alma L., Rasband, Matthew N.
Published in Nat Commun (2020)

Efficient, Long-term Hepatic Gene Transfer Using Clinically Relevant HDAd Doses by Balloon Occlusion Catheter Delivery in Nonhuman Primates

by Brunetti-Pierri, Nicola, Stapleton, Gary E, Law, Mark, Breinholt, John, Palmer, Donna J, Zuo, Yu, Grove, Nathan C, Finegold, Milton J, Rice, Karen, Beaudet, Arthur L, Mullins, Charles E, Ng, Philip
Published 2008

Nitric oxide modulates bone anabolism through regulation of osteoblast glycolysis and differentiation

by Jin, Zixue, Kho, Jordan, Dawson, Brian, Jiang, Ming-Ming, Chen, Yuqing, Ali, Saima, Burrage, Lindsay C., Grover, Monica, Palmer, Donna J., Turner, Dustin L., Ng, Philip, Nagamani, Sandesh C.S., Lee, Brendan
Published in J Clin Invest (2021)