Lanean...
Production of CRISPR/Cas9-Mediated Self-Cleaving Helper-Dependent Adenoviruses
Prolonged expression of CRISPR/Cas9 raises concerns about off-target cleavage, cytotoxicity, and immune responses. To address these issues, we have developed a system to produce helper-dependent adenoviruses that express CRISPR/Cas9 to direct cleavage of the vectors’ own genome after transduction of...
Gorde:
| Argitaratua izan da: | Mol Ther Methods Clin Dev |
|---|---|
| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society of Gene & Cell Therapy
2019
|
| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6506437/ https://ncbi.nlm.nih.gov/pubmed/31080846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.04.003 |
| Etiketak: |
Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|