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Potential of helper-dependent Adenoviral vectors in CRISPR-cas9-mediated lung gene therapy

Since CRISPR/Cas9 was harnessed to edit DNA, the field of gene therapy has witnessed great advances in gene editing. New avenues were created for the treatment of diseases such as Cystic Fibrosis (CF). CF is caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene....

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Bandara, Ranmal Avinash, Chen, Ziyan Rachel, Hu, Jim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305863/
https://ncbi.nlm.nih.gov/pubmed/34301308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-021-00662-w
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