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Efficient Editing of an Adenoviral Vector Genome with CRISPR/Cas9

Immunotherapy based on genetic modification of T cells has played an important role in the treatment of tumors and viral infections. Moreover, adenoviral vectors engineered with improved safety due to their inability to integrate into the host genome have been key in the clinical application of T ce...

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Dettagli Bibliografici
Pubblicato in:Indian J Microbiol
Autori principali: Li, Qiang, Wang, Hui, Gong, Chen-yu, Chen, Zhao, Yang, Jia-xing, Shao, Hong-wei, Zhang, Wen-feng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer India 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7810804/
https://ncbi.nlm.nih.gov/pubmed/33505098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12088-020-00905-3
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