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Potential of helper-dependent Adenoviral vectors in CRISPR-cas9-mediated lung gene therapy

Since CRISPR/Cas9 was harnessed to edit DNA, the field of gene therapy has witnessed great advances in gene editing. New avenues were created for the treatment of diseases such as Cystic Fibrosis (CF). CF is caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene....

Полное описание

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Библиографические подробности
Опубликовано в: :Cell Biosci
Главные авторы: Bandara, Ranmal Avinash, Chen, Ziyan Rachel, Hu, Jim
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305863/
https://ncbi.nlm.nih.gov/pubmed/34301308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-021-00662-w
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