Subretinal gene delivery using helper-dependent adenoviral vectors

This study describes the successful delivery of helper-dependent adenoviral vectors to the mouse retina with long term and robust levels of reporter expression in the retina without apparent adverse effects. Since these vectors have a large cloning capacity, they have great potential to extend the s...

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Bibliographic Details
Main Authors: Wu, Linda, Lam, Simon, Cao, Huibi, Guan, Rui, Duan, Rongqi, van der Kooy, Derek, Bremner, Rod, Molday, Robert S, Hu, Jim
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Methodology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125205/
https://ncbi.nlm.nih.gov/pubmed/21711866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-1-15
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