Efficient Gene Delivery to Pig Airway Epithelia and Submucosal Glands Using Helper-Dependent Adenoviral Vectors

Airway gene delivery is a promising strategy to treat patients with life-threatening lung diseases such as cystic fibrosis (CF). However, this strategy has to be evaluated in large animal preclinical studies in order to translate it to human applications. Because of anatomic and physiological simila...

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Detalhes bibliográficos
Main Authors: Cao, Huibi, Machuca, Tiago N, Yeung, Jonathan C, Wu, Jing, Du, Kai, Duan, Cathleen, Hashimoto, Kohei, Linacre, Virginia, Coates, Allan L, Leung, Kitty, Wang, Jian, Yeger, Herman, Cutz, Ernest, Liu, Mingyao, Keshavjee, Shaf, Hu, Jim
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Methods - Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890457/
https://ncbi.nlm.nih.gov/pubmed/24104599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.55
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