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Ex Vivo Adenoviral Vector Gene Delivery Results in Decreased Vector-associated Inflammation Pre- and Post–lung Transplantation in the Pig

Acellular normothermic ex vivo lung perfusion (EVLP) is a novel method of donor lung preservation for transplantation. As cellular metabolism is preserved during perfusion, it represents a potential platform for effective gene transduction in donor lungs. We hypothesized that vector-associated infla...

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Detalhes bibliográficos
Main Authors: Yeung, Jonathan C, Wagnetz, Dirk, Cypel, Marcelo, Rubacha, Matthew, Koike, Terumoto, Chun, Yi-Min, Hu, Jim, Waddell, Thomas K, Hwang, David M, Liu, Mingyao, Keshavjee, Shaf
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369301/
https://ncbi.nlm.nih.gov/pubmed/22453765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.57
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