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Potential of helper-dependent Adenoviral vectors in CRISPR-cas9-mediated lung gene therapy

Since CRISPR/Cas9 was harnessed to edit DNA, the field of gene therapy has witnessed great advances in gene editing. New avenues were created for the treatment of diseases such as Cystic Fibrosis (CF). CF is caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene....

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Foilsithe in:Cell Biosci
Main Authors: Bandara, Ranmal Avinash, Chen, Ziyan Rachel, Hu, Jim
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305863/
https://ncbi.nlm.nih.gov/pubmed/34301308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-021-00662-w
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