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Potential of helper-dependent Adenoviral vectors in CRISPR-cas9-mediated lung gene therapy

Since CRISPR/Cas9 was harnessed to edit DNA, the field of gene therapy has witnessed great advances in gene editing. New avenues were created for the treatment of diseases such as Cystic Fibrosis (CF). CF is caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene....

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Publicat a:Cell Biosci
Autors principals: Bandara, Ranmal Avinash, Chen, Ziyan Rachel, Hu, Jim
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305863/
https://ncbi.nlm.nih.gov/pubmed/34301308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-021-00662-w
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