Mapping axon initial segment structure and function by multiplexed proximity biotinylation

Axon initial segments (AISs) generate action potentials and regulate the polarized distribution of proteins, lipids, and organelles in neurons. While the mechanisms of AIS Na(+) and K(+) channel clustering are understood, the molecular mechanisms that stabilize the AIS and control neuronal polarity...

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Vydáno v:Nat Commun
Hlavní autoři: Hamdan, Hamdan, Lim, Brian C., Torii, Tomohiro, Joshi, Abhijeet, Konning, Matthias, Smith, Cameron, Palmer, Donna J., Ng, Philip, Leterrier, Christophe, Oses-Prieto, Juan A., Burlingame, Alma L., Rasband, Matthew N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941957/
https://ncbi.nlm.nih.gov/pubmed/31900387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13658-5
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